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Drug Side Effects

Water Retention: A Common Side Effect Of TZDs

Jun 6, 2017

Water retention is a common side effect of Thiazolidinediones (TZDs) and it can lead to complications such as swelling, edema, body heaviness, or constant inactivity. Our body’s well-regulated salt balance depends upon the body type and the diet we follow. TZDs can disturb this function and increase the retention of corrosive salt by our kidneys. As a result, our body starts retaining water to keep the salt diluted. The excess water then seeps out of the blood vessels due to excessive pressure on the circulatory system.

Symptoms Of Water Retention

  •  Sudden weight gain is the most common sign of your body retaining more water than it requires
  • Another tell-tale sign of edema is swelling of the hands, feet, and ankles, especially after a day where you’ve stood for a long period
  • Heaviness in the breast
  • Bloating in the abdominal region
  • Indentations left on the skin, on being pressed

What Helps In Reducing Water Retention Caused By TZDs?

  • Following a diet that is low in sodium
  • Eating more magnesium and potassium-rich food
  • Taking Vitamin-B6 supplements
  • Elevating your feet from time to time, if your job requires you to stand or sit for too long

If water retention persists, you should consult a doctor for specific advice for your condition.

Sharda Agarwal
Sharda Agarwal is a qualified Functional Nutrition Therapy Practitioner & a Certified Blood Chemistry Analyst. She first used dietary supplements to overcome a debilitating migraine she suffered for years. Since then she has studied the subjects of nutrition and nutrients extensively. She uses this to manage the health of her family at home and with Sepalika.